POLYNUCLEOTIDES
Polynucleotides are bio-stimulating injectables derived from purified DNA fragments. They don’t add volume — they help the skin repair, regenerate and renew from within.
Particularly effective for delicate areas like the under-eye, PN treatments work by stimulating fibroblasts, boosting collagen and elastin, and reducing inflammation. The result is fresher, firmer, brighter skin — gradual, natural, and built to last.
Support your skin’s own repair and regeneration.
A GENTLE FIT
A short read to help you decide whether a consultation makes sense for you
Your under-eyes look tired, dark or fragile, and skincare alone is not making enough difference.
Fine lines or crepey texture are starting to affect delicate facial areas.
You want gradual skin improvement without adding volume or changing your features.
A natural-looking result matters more to you than a dramatic change.
You want gradual, natural improvement over weeks — not an instant dramatic change
WHAT DOES IT HELP WITH
Dark circles
Fine lines
Skin laxity
Under-eye skin quality
Fragile skin
Dehydrated skin
THE ESSENTIALS
Purified polynucleotides are injected into the skin where they stimulate fibroblasts — the cells responsible for producing collagen and elastin.
They also improve hydration and reduce inflammation, making them ideal for sensitive and delicate zones.
Smoother, firmer, brighter skin with improved quality and texture.
Under-eyes look less tired, more rested.
2–3 sessions, 2–4 weeks apart.
Maintenance every 6–9 months.
Minimal. Mild redness at injection points resolves within hours.
At NAYMA, we use Ameela polynucleotide treatments to support skin quality, repair and regeneration.
They may be particularly useful in areas where the skin is delicate, thin or showing early signs of ageing.
One session
May be suitable depending on your previous treatment and individual plan.
Course of two
Because polynucleotides work gradually, a short course may be recommended where more sustained skin regeneration is the goal.
REAL RESULTS

Improved skin quality after a course of treatment.

A fresher, less tired-looking under-eye area.

Smoother-looking skin with improved texture.
CONSULTATION FIRST
The under-eye area is particularly complex. Tired-looking eyes can be caused by skin quality, pigmentation, hollowing, anatomy — or a combination.
We identify the cause before recommending polynucleotides, filler, skin boosters or no injectable treatment at all.
What may be causing it
Which treatment fits
How many sessions
What to combine it with
WHY NAYMA
Dr María Padilla and Dr Nayra Noble are experienced dentists with advanced training in facial aesthetics. Every treatment at Nayma begins with a proper consultation — focused on what will genuinely work for you, not what sells.
A calm clinic space. Thoughtful treatments. No pressure. Just honest advice.
FAQ
Purified DNA fragments, most commonly derived from salmon. They are biocompatible — recognised by the body and well tolerated.
No. Polynucleotides don’t add volume. They stimulate the skin’s own repair and regeneration — the improvement comes from within.
Yes — it’s one of their most effective treatment zones. The regenerative effect works particularly well on thin, delicate skin.
Profhilo® provides deep hydration and bio-remodelling across a larger area. PN treatments are more targeted — ideal where repair and regeneration are the priority.
FROM £210
Unit 1 Teach House, Gilbert Drive, Boston, Lincolnshire PE21 7TQ · Convenient parking available
OFTEN COMBINED WITH
Restore volume and contour where clinically appropriate.
Improve hydration, firmness and skin quality without adding volume.
Deep hydration for smoother, healthier-looking skin.